Skip to main content
Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer

Fig. 1

Overexpressed PES1 might be one of the prognostic biomarkers for pancreatic cancer. a, the mRNA expression level analysis of PES1 in pancreatic cancer patient specimens (n = 179) and pancreatic non-tumor tissues (n = 171) by using the GEPIA web tool (http://gepia.cancer-pku.cn/). *, P < 0.05. b, typical IHC image of PES1 in pancreatic tissue microarray (pancreatic non-tumor tissue n = 21, pancreatic cancer n = 35). c, IHC scores of PES1 in pancreatic tissue microarray (pancreatic non-tumor tissue n = 21, pancreatic cancer n = 35), P < 0.001. d, the expression level of PES1 analyzed by Western Blotting from 11 pair of pancreatic cancer patient specimens and adjacent non-tumor tissues. P = 0.01. e, HPDE6-C7, PANC-1, AsPC-1,SW1990, BxPC-3 and MIA PaCa-2 cells were harvested for Western Blotting and RT-qPCR analysis. Data presented as Means ± SD (n = 3). **, P < 0.01; ***, P < 0.001. f, the disease free survival time and overall survival time of pancreatic cancer patients with different expression level of PES1 was determined by GEPIA, P values as indicated

Back to article page