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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via JAK2/STAT3 cascade

Fig. 1

HOTAIR and ST6GAL1 are upregulated during CRC progression. a Differential HOTAIR expression was detected between CRC tissues and the corresponding non-tumor tissues. b High HOTAIR level was determined in advanced CRC stages. c Overexpressed HOTAIR was identified in CRC patients with metastasis. d HOTAIR expression was also identified in CRC cell lines by qRT-PCR. e Upregulation of ST6GAL1 was detected in CRC tissues. f ST6GAL1 expression was higher in advanced CRC patients. g High ST6GAL1 expression was shown in CRC samples with metastasis. h ST6GAL1 level was detected of CRC cell lines by qRT-PCR. i ST6GAL1 expression was also identified in CRC cell lines by western blot. j The Kaplan-Meier overall survival curves (OS) was illustrated on the basis of HOTAIR and ST6GAL1 expression. Data were the means ± SD of triplicate determinants (*P < 0.05)

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