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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Exosomal lncRNA ZFAS1 regulates esophageal squamous cell carcinoma cell proliferation, invasion, migration and apoptosis via microRNA-124/STAT3 axis

Fig. 2

Disturbing the expression of ZFAS1 represses the proliferation, migration and invasion of ESC cells and promote their apoptosis. a: Interference efficiency of ZFAS1 in Eca109 cells determined by RT-qPCR. b: RT-qPCR detected miR-124 expression in Eca109 cells. c: Proliferation of Eca109 cells using EdU assay. d: Colony formation ability using colony formation assay. e: Apoptosis of Eca109 cells in each group using flow cytometry. f: Migration of Eca109 cells in each group using scratch test. g: Invasion of Eca109 cells in each group using Transwell assay. h: Tumor volume growth curve in each group, n = 5. sh-NC group: Eca109 cells transfected with sh-ZFAS1 plasmid NC, sh-ZFAS1 group: Eca109 cells transfected with sh-ZFAS1 plasmid. * p < 0.05 vs. the sh-NC group. Measurement data were depicted as mean ± standard deviation; comparisons between two groups were conducted by independent sample t-test, and comparisons among multiple groups were assessed by one-way analysis of variance followed by Tukey’s post hoc test; Repetitions = 3 in cellular experiment

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