Fig. 6

NDRG1 overexpression inhibited tumor growth in vivo. a Morphological observation of tumors formed after injection of nude mice with HCT116 cell lines that with NDRG1 overexpression or silencing. b Average volumes of xenografts, (c) growth curves of tumors, and (d) weight of tumors taken from nude mice after 30 days of growth. e The representative IHC staining images of NDRG1, p21, and Ki-67 in tumor xenografts. Error bar represents the mean ± SD of four or five independent experiments. ***p < 0.001, ****p < 0.0001