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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21

Fig. 7

p21 could reverse the increased tumor growth induced by NDRG1 silencing in vivo. a and (b) Morphological observation of xenografts in sh-Control, SH-NDRG1, and SH-NDRG1/p21 groups. c Tumor volume and (d) Tumor weight were quantified in three groups. Error bar represents the mean ± SD of five independent experiments. ***p < 0.001, ****p < 0.0001

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