N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21

Table 1 The relationship betwee NDRG1 expression and clinical features in this study

Variable	case	NDRG1 expresssion		P value
Variable	case	Positive	Negative	P value
Tissue				< 0.0001
Normal	89	53	36
Cancer	89	26	63
Age				0.068
≤ 60	39	12	27
> 60	50	25	25
Gender				0.399
Male	48	18	30
Femal	41	19	22
Lymphatic invasion				0.009
N0	48	26	22
N1 + N2	41	11	30
Local invasion				0.019
T1 + T2	47	25	22
T3 + T4	42	12	30
TNM stage				0.087
I + II	37	18	19
III + IV	52	16	36
Tumor Diameter				< 0.001
≤ 3 cm	31	16	15
> 3 cm	58	10	48

ISSN: 1756-9966