Fig. 2
From: RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer
KHSRP promoted NSCLC cell proliferation, migration and invasion. a The migration and invasion abilities of the four human lung cancer cell lines were assessed by Transwell assays. b The levels of KHSRP expression in 4 human NSCLC cell lines were measured by real-time PCR and Western blotting. c The mRNA and protein levels of KHSRP in KHSRP knockdown and negative control A549 cells as well as in KHSRP overexpression and control NCI-H292 cells were determined by real-time PCR and Western blotting analyses, respectively. d The effect of KHSRP on cell proliferation was evaluated by a CCK-8 assay in A549 and NCI-H292 cells. e Wound-healing assays were performed in A549 and NCI-H292 cells. f The effect of KHSRP on cell migration was assessed by Transwell migration assays in A549 and NCI-H292 cells. g The effect of KHSRP on cell invasion was assessed by Matrigel invasion assays in A549 and NCI-H292 cells