Fig. 5
From: Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth
Overexpression of circRHOBTB3 partly reversed miR-654-3p-induced proliferation of GC cells. a, b cck8 assay, c colony formation assay were performed to evaluate the ability of proliferation in overexpressed circRHOBTB3 AGS and HGC27 cell lines transfected with miR654-3p or NC-mimiR. d, e Cell cycle distribution was analyzed by flow cytometry. # vs control group, * vs miR-654-3p group. f p21 protein expression was determined by western blot. g Mode pattern of circRHOBTB3/miR-654-3p/p21 regulatory network. The data was expressed as mean ± SD of at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. #p < 0.05, # #p < 0.01