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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Human bone marrow mesenchymal stem cells-derived microRNA-205-containing exosomes impede the progression of prostate cancer through suppression of RHPN2

Fig. 7

GW4869 suppresses the production of exosomes from hBMSCs, thus reducing the delivered exosomal miR-205. a release of exosomes from hBMSCs in cells treated with GW4869 or DMSO detected using Ach E activity assay; b miR-205 expression in LNCaP cells treated with MSC medium following or without GW4869 treatment as measured using RT-qPCR; c migration and invasion of LNCaP cells treated with MSC medium following or without GW4869 treatment as measured using Transwell assay (× 200). *, p < 0.05. Measurement data were expressed as mean ± standard deviation; comparisons between two groups were analyzed using unpaired t-test; the experiment was repeated three times independently

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