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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway

Fig. 6

The expression of ITGA2 was positively correlated with PD-L1 in malignant cancer patient specimens. a. IHC Images of ITGA2 and PD-L1 staining using TMA tissue sections (n = 31 PDAC). The scale bars were shown as indicated. b and c. Heatmap (b) and dot plot (c) to show the correlation of IHC scores for the expression of the PD-L1 and ITGA2 proteins in PDAC patient specimens. (r = 0.6352 for spearman correlation coefficients, P < 0.001). d. The GEPIA web tool was searched for the correlation between the expression of PD-L1 and ITGA2 in mRNA levels in malignant cancer samples. P values as indicated in the figure

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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