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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Combination of the natural compound Periplocin and TRAIL induce esophageal squamous cell carcinoma apoptosis in vitro and in vivo: Implication in anticancer therapy

Fig. 1

The effects of CPP and TRAIL alone or in combination on the viability of ESCC cells. a. ESCC cells (YES-2, KYSE-150 and KYSE-510) were treated with various concentrations of CPP and DMSO (< 0.01%) for 24 h or 48 h. Cell viability was determined by MTS assay. Data are shown as the mean ± SEM. *P < 0.05 compared to the untreated cell group. b. ESCC cells (YES-2, KYSE-150 and KYSE-510) were treated with various concentrations of TRAIL for 24 h and 48 h. Cell viability was determined by MTS assay. Data are shown as the mean ± SEM. c. ESCC cells (YES-2, KYSE-150 and KYSE-510) were treated with various concentrations of CPP alone or in combination with TRAIL for 24 h. Cell viability was detected by MTS assay. The Q values represents the combination index. Q values of more than 1.15 suggest a synergism in the combined treatment. Data are shown as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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