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Table 1 Correlation of the expression of CD44v6 and MSI2 with clinical-pathological variables in HCC patients

From: Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway

Clinical-Pathological Variables

Low CD44v6 (n = 43)

High CD44v6(n = 39)

P-value

Low MSI2(n = 37)

High MSI2(n = 45)

P-value

Age(years)

 Young(≤median,48)

27

20

P = 0.293

22

25

P = 0.722

 Old(>median,48)

16

19

 

15

20

AFP(ng/ml)

 Low(≤20)

8

13

P = 0.127

11

10

P = 0.438

 High(>20)

35

26

 

26

35

HBsAg

 Negative

9

3

P = 0.090

7

5

P = 0.320

 Positive

34

36

 

30

40

 

GGT(U/I)

 Low(≤50)

10

17

P = 0.050

10

17

P = 0.303

 High(>50)

33

22

 

27

28

 

Tumor Differentiation

 Well differentiated

10

7

P = 0.554

13

4

**P = 0.004

 Moderately to poorly differentiated

33

32

 

24

41

 

Vascular Invasion

 Absence

34

34

P = 0.330

30

38

P = 0.687

 Presence

9

5

 

7

7

 

Tumor Size

 Small(≤5 cm)

21

13

P = 0.155

11

23

P = 0.051

 Large(>5 cm)

22

26

 

26

22

 

Lymph Node Metastasis

 Absence

40

34

P = 0.373

32

42

P = 0.298

Presence

3

5

 

5

3

 

TNM stagea

 Early stage (I—II)

21

10

*P= 0.031

11

20

P = 0.171

 Advanced stage (III—IV)

22

29

 

26

25

 
  1. a AJCC/UICC T staging system
  2. *P < 0.05, **P<0.01,Significant difference, (χ2 test and Fisher’s exact test)