Table 2 Association of miR-15b-3p Expression in GC with Different Clinicopathological Features
Variables | Exo-miR-15b-3p expression | P-value | |
|---|---|---|---|
Low(n = 54) | High(n = 54) | ||
Age, years | Â | Â | 0.425 |
 <60 | 22(40.7%) | 18(33.3%) |  |
 ≥ 60 | 32(59.3%) | 36(66.7%) |  |
Gender | Â | Â | 0.661 |
 Male | 41(75.9%) | 39(72.2%) |  |
 Female | 13(24.1%) | 15(27.8%) |  |
Smoking | Â | Â | 0.311 |
 Yes | 16(29.6%) | 21(38.9%) |  |
 No | 38(70.4%) | 33(61.1%) |  |
Alcohol abuse | Â | Â | 0.024* |
 Yes | 8(14.8%) | 18(33.3%) |  |
 No | 46(85.2%) | 36(66.7%) |  |
Family history of cancer | Â | Â | 0.206 |
 Yes | 7(13.0%) | 12(22.2%) |  |
 No | 47(87.0%) | 42(77.8%) |  |
Size, cm | Â | Â | 0.020* |
 <3.5 | 30(55.6%) | 18(33.3%) |  |
 ≥ 3.5 | 24(44.4%) | 36(66.7%) |  |
Location | Â | Â | 0.267 |
 Cardia | 16(29.6%) | 11(20.4%) |  |
 Non-cardia | 38(70.4%) | 43(79.6%) |  |
Lauren’s classification |  |  | 0.101 |
 Intestinal type | 22(40.7%) | 14(25.9%) |  |
 Diffuse type | 20(37.0%) | 31(57.4%) |  |
 Mixed type | 12(22.2%) | 9(16.7%) |  |
Histological grade | Â | Â | 0.011* |
 Well differentiated | 22(40.7%) | 10(18.5%) |  |
 Poor differentiated | 32(59.3%) | 44(81.5%) |  |
Invasion depth | Â | Â | 0.176 |
 T1/2 | 28(51.9%) | 21(38.9%) |  |
 T3/4 | 26(48.1%) | 33(61.1%) |  |
Tumor stage | Â | Â | 0.002* |
 I,II | 38(70.4%) | 22(40.7%) |  |
 III,IV | 16(29.6%) | 32(59.3%) |  |
Lymphovascular invasion | Â | Â | 0.001* |
 Negative | 37(68.5%) | 20(37.0%) |  |
 Positive | 17(31.5%) | 34(63.0%) |  |