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Table 2 Association of miR-15b-3p Expression in GC with Different Clinicopathological Features

From: Exosomal transfer of miR-15b-3p enhances tumorigenesis and malignant transformation through the DYNLT1/Caspase-3/Caspase-9 signaling pathway in gastric cancer

VariablesExo-miR-15b-3p expressionP-value
Low(n = 54)High(n = 54)
Age, years  0.425
 <6022(40.7%)18(33.3%) 
 ≥ 6032(59.3%)36(66.7%) 
Gender  0.661
 Male41(75.9%)39(72.2%) 
 Female13(24.1%)15(27.8%) 
Smoking  0.311
 Yes16(29.6%)21(38.9%) 
 No38(70.4%)33(61.1%) 
Alcohol abuse  0.024*
 Yes8(14.8%)18(33.3%) 
 No46(85.2%)36(66.7%) 
Family history of cancer  0.206
 Yes7(13.0%)12(22.2%) 
 No47(87.0%)42(77.8%) 
Size, cm  0.020*
 <3.530(55.6%)18(33.3%) 
 ≥ 3.524(44.4%)36(66.7%) 
Location  0.267
 Cardia16(29.6%)11(20.4%) 
 Non-cardia38(70.4%)43(79.6%) 
Lauren’s classification  0.101
 Intestinal type22(40.7%)14(25.9%) 
 Diffuse type20(37.0%)31(57.4%) 
 Mixed type12(22.2%)9(16.7%) 
Histological grade  0.011*
 Well differentiated22(40.7%)10(18.5%) 
 Poor differentiated32(59.3%)44(81.5%) 
Invasion depth  0.176
 T1/228(51.9%)21(38.9%) 
 T3/426(48.1%)33(61.1%) 
Tumor stage  0.002*
 I,II38(70.4%)22(40.7%) 
 III,IV16(29.6%)32(59.3%) 
Lymphovascular invasion  0.001*
 Negative37(68.5%)20(37.0%) 
 Positive17(31.5%)34(63.0%) 
  1. *P < 0.05