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Table 2 Univariate and Multivariate cox-regression analyses of prognostic factors for gastric cancer

From: Complement C3 overexpression activates JAK2/STAT3 pathway and correlates with gastric cancer progression

Factor

Number

5-year OS

Univariate analysis

Multivariate regression a

Cumulative Rate(%)

OR(95%CI)

P-value

OR(95%CI)

P-value

Age (≥65:< 65 years)

24:82

34.0:40.5

0.948(0.520–1.727)

0.978

  

BMI (≥25.0:< 25.0 kg/m2)

13:93

35.9:39.5

0.916(0416–2.018)

0.842

  

Gender (Male:Female)

65:41

40.4:37.6

1.355(0.807–2.275)

0.230

  

Blood Type (A:AB:B:O)

43:10:22:30

44.4:15.6:46.4:34.2

1.092(0.496–2.405)

0.936

  

Tumor location (GEJ:Upper:Middle:Lower third)

5:27:28:46

26.7:20.2:46.4:51:1

0.988(0.915–1.067)

0.705

  

Surgical resection (Proximal:Distal:Total)

13:45:48

35.9:46.6:32.4

1.143(0.776–1.682)

0.538

  

TNM stage (I + II:III + IV)

37:69

67.9:23.4

3.336(2.205–5.049)

0.001

2.609(1.725–4.194)

< 0.001

Histology (Well:Moderate:Poor)

7:19:80

33.3:46.4:40.3

1.154(0.761–1.750)

0.128

1.049(0.653–1.686)

0.844

IHC C3 score (Low:High))

41:65

52.6:29.7

2.109(1.198–3.714)

0.005

1.848(1.015–3.363)

0.045

Plasma C3 (Low:Normal)

40:66

22.9:47.2

1.730(1.034–2.897)

0.062

1.801(1.049–3.090)

0.033

CEA (Normal:Elevated)

81:25

48.5:7.4

2.673(1.556–4.592)

0.005

1.225(0.680–2.208)

0.500

Morbidity b (Yes:No)

59:47

72.3:5.2

4.799(2.669–8.628)

< 0.001

2.770(1.446–5.305)

0.002

  1. aThose factors were qualified from the univariate analysis of overall survival, which their P values were less than 0.20. b Any postoperative complication was considered as morbidity and pooled together for survival comparison. Abbreviations: OS, overall survival; DFS, disease-free survival; OR, odds ratio; CI, confidential intervals; BMI, body mass index; SLRC, SMA-guided laparoscopic right hemicolectomy; CLRC, conventional laparoscopic right hemicolectomy.