Fig. 5

CLDN6 inhibits breast cancer metastasis through SENP1/HIF-1α signalling in vivo. a Bioluminescence analysis of lung metastasis derived from MDA-MB-231 cells. b The ratio of the human HK2 gene to mouse 18S rRNA in genomic DNA from mouse peripheral blood was used to reflect the amount of circulating tumour cells. c Representative examples of lungs with metastatic foci are shown, and the average number of lung metastases in each group is shown. d Representative HE staining of lung sections is shown. Scale: 100um. * p < 0.05