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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Mesenchymal stromal cells mediated delivery of photoactive nanoparticles inhibits osteosarcoma growth in vitro and in a murine in vivo ectopic model

Fig. 2

AlPcS4@FNPs internalization and retention analysis. Representative flow cytometry analysis of AlPcS4@FNPs (90 μg/mL) loaded MSCs over time (0, 24, 48, 72 h) (a). Representative images of FNPs internalization in MSCs after 1 h loading (0 h) over the time (up to 72 h) by confocal microscope (merge images of green (FITC of FNP) and blue (Hoechst, nuclei) channels are shown) (scale bar = 200 μm) (b). Representative images and quantification of cells migrated through the porous membrane of a Boyden chamber, in absence (0.2% BSA) or presence (20%FBS) of chemotactic stimuli; MSCs loaded with 90 μg/mL AlPcS4@FNPs were compared to unloaded MSCs (c). All data are expressed as mean ± SD (n = 3)

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