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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Molecular interplay between linc01134 and YY1 dictates hepatocellular carcinoma progression

Fig. 1

Knockdown of linc01134 can dampen HCC cell proliferation in vitro and suppress tumor growth in vivo. a The expression of linc01134 in LIHC tissues and para-tumor tissues based on starBase. b Kaplan-Meier analysis demonstrated the effects of linc01134 expression on LIHC patients’ overall survival. c qRT-PCR assay detected linc01134 expression in HCC tissues and para-tumor tissues. d Linc01134 expression in one normal cell line (QSG-7701) and four HCC cell lines (SNU-449, HepG2, HLF and Huh-7) was analyzed by qRT-PCR. e qRT-PCR was used to evaluate the transfection efficiency of linc01134 knockdown. f CCK-8 was performed to study cell viability after knockdown of linc01134. g-h. Colony formation and EdU were performed to assess cell proliferation when down-regulating linc01134. i Flow cytometry evaluated cell apoptosis after knockdown of linc01134. j Xenograft growth curve between sh-NC and sh-linc01134 groups. k-l Tumor volume and weight were measured between sh-NC and sh-linc01134 groups. m IHC analysis was performed to detect Ki-67 positive cells. **P < 0.01

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