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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation

Fig. 6

CUL7 silencing inhibits tumorigenesis in vivo. a, b Bioluminescence imaging showed the tumor size as days elapsed. c Weights of two groups of mice were measured every two days. d H&E staining of sections from mouse brains with U87MG control or sh-CUL7 xenografts at 15 days after implantation with 3 × 106 cells. (scale bar = 200 μm) e Survival analysis for animals implanted with U87MG sh-CUL7 or control cells (P < 0.01 by log-rank test; n control = 6, n sh-CUL7 = 6). f, g IHC for CUL7, MST1, Ki-67 and N-cadherin in sections from indicated xenografts (scale bar = 100 μm). Data are represented as the mean ± SEM

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