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Table 1 Correlation of CUL7 expression in human glioma patients with different clinicopathological features. P values were determined by the Chi-square and Fisher’s exact tests

From: Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation

Variable   CUL7 high expression CUL7 low expression p value
Age ≥45 218 114 < 0.001
< 45 95 190  
Gender Male 183 178 0.983
Female 130 126  
KPS ≥80 161 154 0.030
< 80 44 23  
WHO grade II 71 145 < 0.001
III 106 135  
IV 136 24  
TCGA subtype Neural 77 36 < 0.001
Proneural 53 186  
Classical 85 2  
Mesenchymal 81 19  
IDH status Mutant 220 317 < 0.001
Wild-type 113 18  
MGMT promotor Methylated 179 299 < 0.001
Unmethylated 129 36  
1p/19q Codeletion 41 128 < 0.001
Non-codeletion 294 208  
TERT expression Not expressed 121 195 < 0.001
Expressed 209 141  
ATRX status Mutant 54 143 < 0.001
Wild-type 273 192