Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation

Table 1 Correlation of CUL7 expression in human glioma patients with different clinicopathological features. P values were determined by the Chi-square and Fisher’s exact tests

Variable		CUL7 high expression	CUL7 low expression	p value
Age	≥45	218	114	< 0.001
Age	< 45	95	190
Gender	Male	183	178	0.983
Gender	Female	130	126
KPS	≥80	161	154	0.030
KPS	< 80	44	23
WHO grade	II	71	145	< 0.001
	III	106	135
	IV	136	24
TCGA subtype	Neural	77	36	< 0.001
	Proneural	53	186
	Classical	85	2
	Mesenchymal	81	19
IDH status	Mutant	220	317	< 0.001
IDH status	Wild-type	113	18
MGMT promotor	Methylated	179	299	< 0.001
MGMT promotor	Unmethylated	129	36
1p/19q	Codeletion	41	128	< 0.001
1p/19q	Non-codeletion	294	208
TERT expression	Not expressed	121	195	< 0.001
TERT expression	Expressed	209	141
ATRX status	Mutant	54	143	< 0.001
ATRX status	Wild-type	273	192

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