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Table 3 Univariate and multivariate Cox regression of CUL7 expression for overall survival in glioma patients

From: Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation

Variable

Univariate Cox Regression

 

Multivariate Cox Regression

 

HR (95% CI)

p

HR (95% CI)

p

Age

4.006 (3.208–5.004)

< 0.001

2.549 (1.673–3.883)

< 0.001

Old vs young

Gender

1.106 (0.926–1.321)

0.27

0.952 (0.700–1.295)

0.754

male vs female

WHO grade

7.175 (5.606–9.182)

< 0.001

3.004 (1.926–4.683)

< 0.001

High- vs low-

TCGA subtype

2.300 (1.882–2.810)

< 0.001

1.582 (1.099–2.278)

0.014

Mesenchymal vs non-mesenchymal

CUL7 expression

6.582 (4.578–9.465)

< 0.001

3.084 (1.918–4.959)

< 0.001

High vs low