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Table 3 Univariate and multivariate Cox regression of CUL7 expression for overall survival in glioma patients

From: Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation

Variable Univariate Cox Regression   Multivariate Cox Regression  
HR (95% CI) p HR (95% CI) p
Age 4.006 (3.208–5.004) < 0.001 2.549 (1.673–3.883) < 0.001
Old vs young
Gender 1.106 (0.926–1.321) 0.27 0.952 (0.700–1.295) 0.754
male vs female
WHO grade 7.175 (5.606–9.182) < 0.001 3.004 (1.926–4.683) < 0.001
High- vs low-
TCGA subtype 2.300 (1.882–2.810) < 0.001 1.582 (1.099–2.278) 0.014
Mesenchymal vs non-mesenchymal
CUL7 expression 6.582 (4.578–9.465) < 0.001 3.084 (1.918–4.959) < 0.001
High vs low