Fig. 2

Effects of hsa_circ_0000326 expression on proliferation, apoptosis and migration in lung adenocarcinoma cells. (a) Hsa_circ_0000326 expression levels were determined by RT-PCR. (b) Effect of hsa_circ_0000326 knockdown on cell proliferation, as determined by CCK-8 assay. (c) Effect of hsa_circ_0000326 knockdown on cell apoptosis. (d) Effect of hsa_circ_0000326 knockdown on cell proliferation, as determined by colony formation assay. (e) Effect of hsa_circ_0000326 knockdown on cell migration. (f) Hsa_circ_0000326 expression levels were determined by RT-PCR. (g) Effect of hsa_circ_0000326 overexpression on cell proliferation, as determined by CCK-8 assay. (h) Effect of hsa_circ_0000326 overexpression on apoptosis. (i) Effect of hsa_circ_0000326 overexpression on cell proliferation, as determined by colony formation assay. (j) Effect of hsa_circ_0000326 overexpression on cell migration. Magnification: 100×. Scale bar = 200 μm. The bars with error bars represent the mean ± SD from three independent experiments. *P < 0.05