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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

Fig. 2

HOST2 promoted proliferation and invasion of TNBC cells in vitro. a, b qRT-PCR was conducted to verify the relative expression of HOST2 in MDA-MB-231 and MDA-MB-468 cells transfected with HOST2-siRNA (si-HOST2). c, d MTT assay was performed to determine the cell viability in MDA-MB-231 and MDA-MB-468 cells after knockdown of HOST2. e, f Representative results of the EDU assay of MDA-MB-231 and MDA-MB-468 cells after knockdown of HOST2. g, h Effects of HOST2 knockdown on cell colony formation ability in MDA-MB-231 and MDA-MB-468 cells. i, j Representative results of transwell invasion assay of MDA-MB-231 and MDA-MB-468 cells after knockdown of HOST2. *P < 0.05, **P < 0.01. All experiments were repeated three times

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