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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

Fig. 4

Let-7b, rather than miR-1266, inhibited TNBC cell proliferation. a Pearson correlation analysis of the correlation of HOST2 expression with let-7b and miR-1266 expression in the 40 TNBC samples. b Let-7b and miR-1266 expression in the 40 collected TNBC tissues compared to matched non-cancerous breast tissues. c Let-7b and miR-1266 expression was effectively modulated in MDA-MB-231 and MDA-MB-468 cells after let-7b/miR-1266 mimics transfection. d Effects of let-7b and miR-1266 overexpression on cell proliferation in MDA-MB-231 and MDA-MB-468 cells detected by MTT assay. e Effects of let-7b and miR-1266 expression on cell colony formation ability in MDA-MB-231 and MDA-MB-468 cells. *P < 0.05, **P < 0.01, ***P < 0.001

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