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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

Fig. 6

Let-7b knockdown counteracted the tumour suppressing effects of si-HOST2 in TNBC cells. a-c Functional rescue experiments were carried out in MDA-MB-231 and MDA-MB-468 cells including MTT assay, colony formation assay, and transwell invasion assay. d Western blot analysis showed that knockdown of HOST2 decreased the expression of STAT3 and this effect was reversed by let-7b inhibitor in MDA-MB-231 and MDA-MB-468 cell lines. *P < 0.05, **P < 0.01, ***P < 0.001

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