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Table 3 Surface Plasmon Resonance Method shows the dissociation constant of PRLR-DbsAb and its control mAb against recombinant target antigen

From: A novel bispecific antibody targeting CD3 and prolactin receptor (PRLR) against PRLR-expression breast cancer

Antibody(Antigen)

Ka(1/Ms)

Kd(1/S)

KD(M)

PRLR mAb(PRLR)

3.98E+5

1.62E-4

4.07E-10

PRLR-DbsAb(PRLR)

2.94E+5

6.79E-4

2.31E-9

CD3 mAb(CD3)

9.92E+5

8.96E-4

9.03E-10

PRLR-DbsAb(CD3)

2.47E+5

2.06E-2

8.36E-8