Table 1 Summary of somatic alterations (SNVs) detected in tDNA and ctDNA
SNVs | (a) shared between tissue and blood | (b) blood only | (a) + (b) | |
|---|---|---|---|---|
type (a) SNVs | patients with type (a) circulating SNVs | type (b) SNVs | patients with types (a) and (b) circulating SNVs | |
NGS (TST) | 12/44 (27.2%) | 9/34 (26.5%) | 12 | 15/34 (44.1%) |
dPCR | 17/34 (50.0%) | 14/34 (41.2%) | 1 | 15/34 (44.1%) |
NGS + dPCR | 17/34 (50.0%) | 14/34 (41.2%) | 12 | 20/34 (58.8%) |