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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis

Fig. 1

The miR-615-3p level is upregulated in breast cancer tissues and breast cancer cell lines and positively correlated with the metastatic ability of breast cancer cells. (a) qRT-PCR analysis of miR-615-3p expression in human breast cancer tissue samples and their matched normal breast tissues from 30 breast cancer patients. (b) In situ hybridization analysis of miR-615-3p expression in human breast cancer tissues and matched normal tissues (scale bars = 100 μm). (c) Relative expression of miR-615-3p in metastases and non-metastases tissues(N (Normal, No metastasis, Metastasis) = 51,31,20 respectively). (d) Relative expression of miR-615-3p with the progression of the clinical stage of breast cancer(N(I, II, III, IV) = 11,10,20,10 respectively). (e) qRT-PCR analysis of miR-615-3p expression in noncancerous human mammary epithelial cells (MCF-10A) and breast cancer cell lines (MCF-7, BT-549, MDA-MB-231, and MDA-MB-468 cells) with different metastatic potential

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