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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells

Fig. 1

EVI5 is upregulated in NSCLC tissues and cell lines. a-b Data obtained from several study groups deposited in the Oncomine database (http://www.oncomine.org) were analysed to compare the differences in EVI5 expression between lung cancer and normal lung tissue. c EVI5 mRNA levels in 40 NSCLC tissues and paired oncancerous lung tissues. d Relative mRNA expression levels of EVI5 in 40 paired NSCLC tissues. The Y axis indicates the log10 transformed fold change in the T/N protein expression ratios of EVI5. The number of each specimen is indicated below the X axis. e Effect of the EVI5 mRNA expression level on overall survival in 1926 NSCLC patients. Kaplan–Meier plots were generated using Kaplan–Meier Plotter (http://www.kmplot.com). f Total RNA and protein were extracted from several cell lines, and the expression of EVI5 at the mRNA and protein levels was measured by qRT-PCR and western blotting, respectively. β-actin was used as the internal control. Bars represent mean ± SD from three independent experiments. Significant differences compared with the control: * P < 0.05; **P < 0.01; ***P < 0.001

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