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Table 1 Correlation between the SNCG expression and clinicopathological characteristics in 312 patients with EOC

From: SNCG promotes the progression and metastasis of high-grade serous ovarian cancer via targeting the PI3K/AKT signaling pathway

Characteristics

No. Patients

SNCG Expression

P value

(n = 312)

Low No. (%)

High No. (%)

 

Age(years)

  < 51.0

169

58 (34.3%)

111 (65.7%)

 

  ≥ 51.0

143

41 (28.7%)

102 (71.3%)

0.285

Ca125 (U/ml)

  < 105

53

26 (49.1%)

27 (50.9%)

 

  ≥ 105

259

73 (28.2%)

186 (71.8%)

0.003

FIGO stage

 I/II

73

40 (54.8%)

33 (45.2%)

 

 III/IV

239

59 (24.7%)

180 (75.3%)

< 0.001

Grade

 1

58

26 (44.8%)

32 (55.2%)

 

 2/3

254

73 (28.7%)

181 (71.3%)

0.018

Histology

 Type I

96

48 (50.0%)

48 (50.0%)

 

 Type II

216

51 (23.6%)

165 (76.4%)

< 0.001

Ascites

 Yes

211

62 (29.4%)

149 (70.6%)

 

 No

101

37 (36.6%)

64 (63.4%)

0.198

Cytoreductive surgery

 Optimal

273

80 (29.3%)

193 (70.7%)

 

 Sub-optimal

39

19 (48.7%)

20 (51.3%)

0.015