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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: ABCA8 is regulated by miR-374b-5p and inhibits proliferation and metastasis of hepatocellular carcinoma through the ERK/ZEB1 pathway

Fig. 1

ABCA8 is reduced in human HCC and predicted poor prognosis. a mRNA levels of ABCA8 were analyzed in 40 HCC tissue samples and compared with adjacent non-tumor samples. b Protein levels of ABCA8 were analyzed in HCC tissue samples and adjacent non-tumor samples. c Relative ABCA8 expression levels in 374 HCC and 51 normal samples from The Cancer Genome Atlas database. d Representative images of ABCA8 expression detected by immunohistochemistry, Scale bars: 100× = 100 μm. e A Kaplan-Meier analysis of overall survival (OS) in patients with different staining of ABCA8. f and g Relative ABCA8 levels in WRL-68 and four HCC cells were analyzed using qPCR and western blotting. Data are means ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. T: tumor; N: adjacent non-tumor

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