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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Circ_0008532 promotes bladder cancer progression by regulation of the miR-155-5p/miR-330-5p/MTGR1 axis

Fig. 4

MiR-155-5p/miR-330-5p inhibits cell invasiveness and can remedy the positive effects of circ_0008532. Representative images (a) and quantification (d) of invaded cells were analyzed using a Transwell Matrigel assay. Representative images (b) and percentage of the original wound area (e) of EJ cells were analyzed using a wound-healing assay. Representative images (c) and quantification (f) of HUVECs cultured on Matrigel-coated plates with conditioned medium from EJ cells. (G-I) MiR-155-5p/miR-330-5p counteracts tumor cell invasion (g), migration (h), and angiogenesis (i) induced by circ_0008532. Data are represented as mean ± SD of three independent experiments (* P < 0.05)

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