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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: TFEB-NF-κB inflammatory signaling axis: a novel therapeutic pathway of Dihydrotanshinone I in doxorubicin-induced cardiotoxicity

Fig. 6

DHT inhibited apoptosis to facilitate the anti-inflammation effect. a The representative photomicrographs of a left ventricle section of the heart showed the expression of Cleaved caspase-3 under different treatment, scale bar = 20 μm. N = 5 per group. b Western blots detected the expressions of Bax and Bcl-2 proteins in heart tissues. N = 5 per group. c The results of Hoechst staining under different treatment, scale bar = 40 μm. N = 12 per group. d Western blots assessed the expressions of Bax and Bcl-2 proteins in H9C2 cells. N = 5 per group. All data were presented as means ± SD in triplicate. *p < 0.05, **p < 0.01, ***p < 0.001 is significantly different as indicated, for values in the DOX group. #p < 0.05, ##p < 0.01 is significantly different as indicated, for values in the DOX + DHT group

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