Skip to main content
Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Transcription activation of circ-STAT3 induced by Gli2 promotes the progression of hepatoblastoma via acting as a sponge for miR-29a/b/c-3p to upregulate STAT3/Gli2

Fig. 2

Circ-STAT3 promoted HB cell proliferation, invasion, migration and stemness characteristic. a qRT-PCR verified depletion efficiency of circ-STAT3. One-way ANOVA. b-c EdU (scale bar: 100 μm) and colony formation assay detected proliferation ability of HB cells by knockdown of circ-STAT3. One-way ANOVA. d-e Transwell (scale bar: 200 μm) and wound healing assay (scale bar: 200 μm) examined invasion and migration ability of cells transfected with sh-circ-STAT3#2/3. One-way ANOVA. f Sphere formation assay (scale bar: 200 μm) revealed sphere formation efficiency of circ-STAT3 silenced cells. One-way ANOVA. g-h qRT-PCR and western blot detected expression of stemness biomarkers in circ-STAT3 silenced cells. One-way ANOVA. **P < 0.01.

Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us