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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis

Fig. 1

LINC00520 was significantly up-regulated in melanoma. a The volcano plot showed the levels of lncRNAs between primary malignant melanoma tissues and ANT. The vertical lines represent 2.0-fold changes, and the horizontal line represents P-value of 0.05. The red dot correspond to the differentially expressed lncRNAs with statistical significance. b The cluster heat map showed differentially expressed lncRNAs over 3.0-fold change in melanoma tissues. c The level of LINC00520 was analyzed in 38 malignant melanoma tissues and ANT. d The LINC00520 levels were detected in the GEO#GSE15605 dataset. e GEPIA (http://gepia.cancer-pku.cn/) was used to detect the expression of LINC00520 in TCGA melanoma dataset. f The expression profile of LINC00520 in human melanoma cell lines (A375, A2058, MeWo, CHL-1, SK-MEL-28) and human epidermal melanocytes (HEMa-LP). Data were expressed as the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001

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