Fig. 1

TCGA in silico analysis. a DNA methylation levels (β-Values) for each probe in specific miR loci, comparing normal and ccRCC samples (TCGA Illumina Infinium Human DNA Methylation 450 array), both in the whole cohort (n = 319 ccRCC) and in matched tumor/normal tissue (n = 160); b TCGA RNA-seq data for miR-30a-5p expression in ccRCC samples compared to normal samples, both patient-unmatched (n = 319 ccRCC) and -matched tumor/normal tissue (n = 71); c Correlation between miR-30a-5p expression and methylation levels for each probe using TCGA dataset for ccRCC tumor samples