Table 1 Clinicopathological features of HPV + ve/−ve OSCC patients and their relationship with miR-550a-3-5p expression
Characteristics | HPV + ve OSCC (n = 25) | HPV-ve OSCC (n = 45) | ||||
|---|---|---|---|---|---|---|
Cases | Low miR-550a-3-5p (%) | P | Cases | Low miR-550a-3-5p (%) | P | |
Age (years) | ||||||
 < 60 | 20 | 10 (50.00) | 0.689 | 21 | 9 (42.86) | 0.300 |
 ≥ 60 | 5 | 3 (60.00) | 24 | 14 (58.33) | ||
Gender | ||||||
 Female | 13 | 8 (61.54) | 0.320 | 17 | 6 (35.29) | 0.098 |
 Male | 12 | 5 (41.67) | 28 | 17 (60.71) | ||
Drink | ||||||
 Yes | 7 | 4 (57.14) | 0.748 | 31 | 15 (48.39) | 0.587 |
 No | 18 | 9 (50.00) | 14 | 8 (57.14) | ||
Smoke | ||||||
 Yes | 5 | 3 (60.00) | 0.689 | 28 | 14 (50.00) | 0.848 |
 No | 20 | 10 (50.00) | 17 | 9 (52.94) | ||
Tumor Size | ||||||
 T1-T2 | 9 | 2 (22.22) | 0.025* | 20 | 8 (40.00) | 0.182 |
 T3-T4 | 16 | 11 (68.75) | 25 | 15 (60.00) | ||
Differentiation | ||||||
 Well | 4 | 2 (50.00) | 0.265 | 14 | 6 (42.86) | 0.438 |
 Moderate | 13 | 5 (38.46) | 19 | 9 (47.37) | ||
 Poor | 8 | 6 (75.00) | 12 | 8 (66.67) | ||
Clinical stage | ||||||
 I-II | 14 | 5 (35.71) | 0.066 | 17 | 8 (47.06) | 0.672 |
 III-IV | 11 | 8 (72.73) | 28 | 15 (53.57) | ||
Nodal metastasis | ||||||
 Yes | 20 | 13 (65.00) | 0.009* | 26 | 13 (50.00) | 0.862 |
 No | 5 | 0 (0) | 19 | 10 (52.63) | ||
Recurrence | ||||||
 Yes | 1 | 1 (100.00) | 0.327 | 8 | 5 (62.50) | 0.477 |
 No | 24 | 12 (50.00) | 37 | 18 (48.65) | ||