Fig. 3

PKM2 Knockdown Affects Cancer Associated Phenotypes: (a) shPKM2 results in significant reduction in glycolysis activity in hypoxia among both TACE responder and non-responder like cell lines. (b) Significant increase in caspase 3/7 activity in hypoxia with shPKM2 in hypoxia. (c) shPKM2 significantly reduced colony formation ability in both responders and non-responders in hypoxia. (d) shPKM2 results in significant reduction in migratory ability in hypoxia but has no effect on invasion ability (e)