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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: ACYP2 contributes to malignant progression of glioma through promoting Ca2+ efflux and subsequently activating c-Myc and STAT3 signals

Fig. 1

Association of increased expression of ACYP2 with poor survival in low-grade glioma (LGG) patients. a, mRNA expression of ACYP2 in normal brain tissues (n = 24) and glioma tissues (n = 52) was analyzed by qRT-PCR assay. Its expression was normalized to 18S rRNA levels. b, Protein expression of ACYP2 in normal brain tissues (N, n = 3) and glioma tissues (T, n = 7) was analyzed by western blot analysis (upper panel). GAPDH was used as a loading control. Quantitative illustration of ACYP2 protein levels are shown in the lower panel. c, Representative images showing immunohistochemistry (IHC) staining of ACYP2 on histologic slides of normal brain tissues and glioma tissues. d, A significant association of increased expression of ACYP2 with poor survival in LGG patients (n = 473; data from TCGA dataset). *, P < 0.05

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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