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Table 1 Association of SALL4 expression with clinicopathological parameters of ccRCC patients (TCGA Renal 2)

From: VHL mutation-mediated SALL4 overexpression promotes tumorigenesis and vascularization of clear cell renal cell carcinoma via Akt/GSK-3β signaling

Parameters Frequency (%) SALL4 expression P value
  < median ≥median
Age (n = 481)
 < 60 222 (46.2) 112 110 0.822
 ≥ 60 259 (53.8) 128 131  
Sex (n = 481)
 Male 313 (65.1) 148 165 0.118
 Female 168 (34.9) 92 76  
T stage (n = 481)
 T1 237 (49.3) 133 104 0.003
 T2 62 (12.9) 35 27  
 T3-T4 182 (37.8) 73 109  
N stage (n = 224)
 N0 207 (92.4) 109 98 0.065
 N1+ 17 (7.6) 5 12  
M stage(n = 461)
 M0 390 (84.6) 203 187 0.051
 M1+ 71 (15.4) 28 43  
Tumor Grade (n = 455)
 Grade 1–2 213 (2.0) 122 91 0.003
 Grade 3 176 (38.7) 86 90  
 Grade 4 66 (14.5) 22 44  
AJCC stage (n = 436)
 Stage I 208 (47.7) 116 92 0.047
 Stage II 48 (11.0) 24 24  
 Stage III 110 (25.2) 51 59  
 Stage IV 70 (16.1) 26 44