Table 2 Cox regression analysis of prognostic factors associated with overall survival of ccRCC patients (n = 200)
Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age | ||||||
< 60 | 1.354 | 0.846–2.168 | 0.207 | – | – | – |
≥ 60 | ||||||
Sex | ||||||
Male | 1.062 | 0.670–1.683 | 0.800 | – | – | – |
Female | ||||||
T stage | ||||||
T1-T2 | 3.529 | 2.217–5.618 | < 0.001 | 2.377 | 0.945–5.983 | 0.066 |
T3-T4 | ||||||
N stage | ||||||
N0 | 2.149 | 1.071–4.312 | 0.031 | 0.726 | 0.332–1.589 | 0.423 |
N1+ | ||||||
M stage | ||||||
M0 | 5.290 | 3.291–8.502 | < 0.001 | 4.375 | 2.381–8.038 | < 0.001 |
M1+ | ||||||
Tumor Grade | ||||||
Grade 1–2 | 2.451 | 1.485–4.047 | < 0.001 | 1.190 | 0.674–2.102 | 0.548 |
Grade 3–4 | ||||||
AJCC stage | ||||||
Stage I-II | 3.776 | 2.326–6.128 | < 0.001 | 0.967 | 0.355–2.639 | 0.948 |
Stage III-IV | ||||||
SALL4 level | ||||||
Low | 2.058 | 1.289–3.285 | 0.003 | 1.844 | 1.129–3.012 | 0.015 |
High | ||||||