Fig. 7From: LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cellsA schematic representation of the function of lncRNA-HOTAIR in the progression of EC by regulating MTHFR. LncRNA HOTAIR downregulated MTHFR expression via elevating MTHFR methylation, thus contributing to enhanced cell proliferation, but inhibited cell apoptosis and the chemosensitivity of EC cells to 5-FUBack to article page