Fig. 4
Impact of the direct correlation between TRF2 and VEGF-A on patients’ survival. Survival analysis of CRC patients stratified on the basis of the levels of VEGF-A and TRF2. a Progression/ Disease Free Survival of patients expressing high levels of VEGF-A and TRF2 (VEGF-AH/TRF2H) was compared with that of patients in which high levels of TRF2 correlate with low VEGF-A expression (VEGF-AL/TRF2H). b Disease Free Survival of stage I-III CRC patients. c and d Progression/ Disease Free Survival of the VEGF-AH/TRF2H and VEGF-AL/TRF2H patients who (c) did not receive (Untreated patients) or (d) did receive (Treated patients) adjuvant therapy. For each sub-population the number of patients is reported in the brackets. Percentages of surviving patients are reported close to the respective curves