Table 2 Univariate analysis

Age(> 67 vs ≤ 67)

1.01 (0.65–1.57; p = 0.97)

Sex(male vs female)

1.35 (0.84–2.17; p = 0.22)

Site(rectum vs colon)

1.86 (1.18–2.95; p = 0.08)

Size(3/4 vs 1/2)

1.50 (0.72–3.12; p = 0.28)

Node(N+ vs N-)

1.63 (1.04–2.57 p = 0.03)

Metastasis(M+ vs M-)

2.89 (1.79–4.68; p < 0.0001)

Grading(3 vs 1/2)

1.25 (0.72–2.17; p = 0.42)

VEGF-A(L vs H)

1.58 (1.01–2.48; p = 0.046)

TRF2(L vs H)

1.13 (0.72–1.77; p = 0.60)

VEGF-A/TRF2(H/H vs others)

1.66 (1.04–2.64; p = 0.032)