Table 2 Univariate and multivariable analysis of OS and DFS of patients with GC
Variable | OS | DFS | ||||
|---|---|---|---|---|---|---|
Univariate analysis P > |z| | Multivariable analysis | Univariate analysis P > |z| | Multivariable analysis | |||
P > |z| | HR (95% CI) | P > |z| | HR (95% CI) | |||
Gender | ||||||
 Male (n = 111) vs. female (n = 60) | 0.290 |  |  | 0.264 |  |  |
Age (years) | ||||||
  ≤ 60 (n = 73) vs. > 60 (n = 98) | 0.787 |  |  | 0.805 |  |  |
Differentiation | ||||||
 Well (n = 18) vs. Moderate/Poor (n = 153) | 0.075 |  |  | 0.073 |  |  |
Tumor diameter (cm) | ||||||
  < 5 (n = 112) vs. ≥5 (59) | 0.015 |  |  | 0.019 |  |  |
Tumor localization | ||||||
 Up (n = 19) vs. Middle/Down (152) | 0.425 |  |  | 0.429 |  |  |
Depth of invasion | ||||||
 T1 + T2 (n = 72) vs. T3 + T4 (n = 99) | < 0.001 | 0.003 | 2.431(1.346-4.390) | < 0.001 | 0.004 | 2.367(1.311-4.274) |
Lymph node metastasis | ||||||
 Negative (n = 79) vs. Positive (n = 92) | < 0.001 | 0.001 | 2.642(1.513-4.615) | < 0.001 | 0.001 | 2.653(1.518-4.637) |
BDH2 expression | ||||||
 Low (n = 127) vs. High (n = 44) | 0.001 | 0.011 | 0.404(0.200-0.815) | 0.001 | 0.017 | 0.426(0.211-0.861) |