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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer

Fig. 2

CYT997 induced cell cycle G2/M arrest and apoptosis in GC cells. a The cell cycle distribution of SGC-7910 and MKN45 cells treated with CYT997 was analyzed by flow cytometry.**p < 0.01. b Expression of Cyclin B1 and p21 was detected by western blotting in SGC-7901 and MKN45 cells treated with CYT997. c Following treatment of SGC-7901 and MKN45 cells in different dose of CYT997 for 24 h, apoptotic cells were detected by Annexin V-FITC and PI double staining. **p < 0.01.d Expression of cleaved caspase 3, caspase 3, cleaved PARP and PARP was detected by western blotting in SGC-7901 and MKN45 cells treated with CYT997

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