Fig. 5

Mitochondrial ROS inhibitor MitoQ reversed the inhibition of CYT997 in GC cells. a SGC-7901 cells were treated with CYT997 alone or in combination with MitoQ (500 nM). Cell viability was detected by a CCK8 assay. b The cell cycle distribution of SGC-7901 cells treated with CYT997 alone or in combination with MitoQ (500 nM) was analyzed by flow cytometry. c SGC-7901 cells were treated with CYT997 alone or in combination with MitoQ (500 nM). Apoptosis was detected by flow cytometry. d Expression of cell cycle, autophagy and apoptosis related proteins was detected by western blotting in SGC-7901 cells