Fig. 8From: Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancerMechanism of CYT997-induced apoptosis in GC cells. CYT997 activated mitochondrial ROS to trigger protective autophagy and inhibited JAK2/STAT3 pathway to induce G2/M arrest and apoptosis in GCBack to article page