Fig. 3

CASC9 promotes cell metastasis of BCCs in vitro and in vivo. a and c The migratory abilities of BCCs were determined using wound healing assay in vitro. b and d The invasive abilities of BCCs were determined using transwell assay in vitro. e The metastasis of BCCs we also determined using whole-body fluorescent imaging system, and knockdown of CASC9 decreased luciferase signals. f Knockdown of CASC9 significantly reduced the number of pulmonary metastases and metastases size. g Knockdown of CASC9 decreased Ki67 expression of BCCs in vivo. The data are shown as the mean ± SD. *P < 0.05; **P < 0.01