Fig. 3
From: Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
Regulatory mechanisms involved in aerobic glycolysis in HCC. Aerobic glycolysis can be regulated by various transcriptional factors, such as HIF-1α and c-Myc, and many signaling pathways, such as AMPK and PI3K/Akt, as well as noncoding RNAs. The regulatory mechanisms include the regulation of enzymes activity and the relative gene expression levels, and both mechanisms are tightly intertwined