Fig. 8From: Human umbilical cord mesenchymal stem cells-derived exosomes deliver microRNA-375 to downregulate ENAH and thus retard esophageal squamous cell carcinoma progressionSchematic diagram showing potential molecular mechanisms by which exosomal miR-375 regulates the progression of ESCC. miR-375 is delivered into ESCC cells via hUCMSCs-exo to decrease expression of ENAH, and subsequently to increase expression of Bax and E-cadherin but to reduce expression of N-cadherin, Snail, Bcl-2 and Bcl-xl, leading to decreased proliferation, invasion and migration and enhanced apoptosis of ESCC cellsBack to article page